Biomed Imaging Interv J 2006; 2(4):e45-29
doi: 10.2349/biij.2.4.e45-29
© 2006 Biomedical Imaging
and Intervention Journal
ABSTRACT
Case Presentation from Various Countries: Case from Thailand
Benjaporn Chaiwun 1, Malai Muttarak 2, Areewan Somwangprasert 3
1 Department of Pathology, Chiang Mai University, Thailand
2 Department of Radiology, Chiang Mai University, Thailand
3 Department of Surgery, Chiang Mai University, Thailand
A 38-year-old woman presented with a right breast mass for 5 years. Her medical history was schizophrenia. There was no familial history of breast carcinoma. Physical examination revealed tense huge breast mass with nodular surface involving almost the entire right breast. The axillary node was not enlarged. Ultrasonography showed multiple dilatation of ducts with nodules in some ducts and a 1-cm solid mass in the right subareola. Mammography showed very dense breast with scattered round calcifications in the right breast.
Provisional diagnosis was papillary tumor, possible juvenile papillomatosis. Fine needle or core biopsy was planned but the patient refused and requested for mastectomy. Simple mastectomy was performed. Final diagnosis was combined intraductal cystic hypersecretory carcinoma (micropapillary, cribiform and solid patterns) with cystic hypersecretory hyperplasia. ER: moderate expression (2+). PGR: strong expression (3+). C-erbB2: no expression. Thyroglobulin: no expression. P53: weak nuclear stain, >10%.
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